Cisplatin, a cancer chemotherapy drug first approved by the FDA in 1978, revolutionized the treatment of many types of cancer.  Despite its effectiveness, in many cases doctors are forced to reduce the drug’s dose, or abandon it altogether, due to serious side effects on patients’ hearing.
Between 10-25% of adults and up to 60% of children [...]

Tags: chemotherapy, children, cisplatin, COMT, hearing loss, TPMT