Nov
03
2009
The “stomach flu” isn’t really the flu at all. It’s actually viral gastroenteritis, and its most common cause is a group of viruses called noroviruses. No matter what you call it, the illness is highly contagious and very unpleasant — symptoms include abdominal pain, vomiting, and diarrhea. In close quarters, a norovirus outbreak can quickly [...]
Tags: CDC, cruise ship, norovirus
Oct
28
2009
Medco Health Solutions, Inc., announced this week that it will conduct a clinical trial to assess whether clopidogrel bisulfate (Plavix®, Bristol-Myers Squibb and Sanofi-aventis) is just as effective as the newer drug prasugrel (Effient™, Eli Lilly and Company) in people who lack a genetic variation that inhibits their metabolism of clopidogrel. This new research has [...]
Tags: clopidogrel, clotting, comparative effectiveness research, CYP2C19, Effient, Francis Collins, heart, Medco, pharmacogenomics, Plavix, prasugrel
Oct
23
2009
There are over 50,000 people in North America who define themselves as Hutterites, though you probably have never met one. One of the main branches of the Anabaptists, Hutterites live in self-sustaining communities throughout the rural northwestern United States and Canada.
Like their sister branches, the Amish and the Mennonites, the history and culture of [...]
Tags: Anabaptist, Haplogroup, Hutterite, Jakob Hutter, mtDNA, Y-chromosome
Oct
15
2009
Here’s how it goes for me: a few afternoons a year, usually when I haven’t slept or eaten right, but sometimes for no apparent reason, I begin to sense a pressure behind my left eyebrow and to feel queasy. By now I know what’s coming, and I resign myself to another miserable evening and a [...]
Tags: 23andWe, headache, migraine, survey
Oct
14
2009
The Near East – a swath of land that encompasses the Arabian Peninsula, the Levant, and everywhere in between – has been populated by humans longer than anywhere else in the world save Africa. It is where agriculture was born and spread into Eurasia. It is where the ancient civilizations of Mesopotamia and Egypt [...]
Tags: Arabia, Bedouin, Haplogroup, J1e, Semitic, Y-chromosome
Oct
09
2009
A segment of chromosome 14 folded to reveal a fractal curve using Origami. Designed and folded by Jason Ku. Photo by Erik Demaine.
How do you get three billion pairs of As, Cs, Ts and Gs—about six feet worth of DNA—into the nucleus of a tiny cell?
Most students of biology would answer by saying [...]
Tags: DNA, fractal, globule, Harvard, MIT, nucleus, Science, structure, UMass
Oct
08
2009
Empress Alexandra Feodorovna and Prince Alexei, 1911.
The princes of early 20th century Europe had a problem. The source of their wealth and power — the royal blood coursing through their veins — could also sentence them to an early death.
A mutation that spontaneously arose in the DNA of Britain’s Queen Victoria doomed many of her [...]
Tags: factor IX, hemophilia, Romanovs, royal disease
Sep
30
2009
Inflammatory bowel disease (IBD), which can appear as either ulcerative colitis or Crohn’s disease, damages the lining of the digestive tract and leads to abdominal cramps, incomplete digestion and nutritional deficiencies.
Previous research on IBD gave researchers reason to suspect that the CD39 gene, which is involved with inflammatory responses and immunity, may play a role [...]
Tags: PNAS, rodent, ulcerative colitis
Sep
25
2009
For as long as humans have lived in complex communities, cities and civilizations, they have divided and classified their societies. Those divisions have been based on age, gender, appearance or – in many cases – occupation. In many traditional societies artisans would share the same social status; as would soldiers, priests and workers in any [...]
Tags: Caste, DNA, India, Nature, SNPs
Sep
24
2009
Glaucoma is the second leading cause of blindness and is estimated to affect over 66 million people worldwide. This group of diseases is typically caused by increased pressure in the eye, which slowly damages the optic nerve and leads to gradual vision loss and eventual, incurable blindness if left untreated.
Tags: African, glaucoma, PNAS, primary open-angle glaucoma