Feb
25
2010
Atrial fibrillation (AF) is the most common irregular heart rhythm, affecting one in four people over the age of 40. While not usually life-threatening on its own, individuals with the condition are at increased risk of stroke and heart failure. AF appears most frequently in older, male individuals with a history of obesity or cardiovascular [...]
Tags: atrial fibrillation
Feb
23
2010
The journal Current Biology has a special review issue on the global genetic history of Homo sapiens. The articles are written for a fairly technical audience, but if it’s a topic you’re interested in, you might want to check it out. All of the articles are available online for free.
Archaeogenetics — Towards a ‘New [...]
Tags: archaeogenetics, Current Biology, evolution, human genetic history
Feb
22
2010
People chronically infected with the hepatitis C virus currently have only one treatment option: a combination of polyethylene glycol (PEG)-ylated interferon alpha and ribavirin (RBV). Not only does this drug regimen fail to eradicate the virus in about half of all patients who receive it, but even when it does work the side effects can [...]
Tags: anemia, hepatitis C, ITPA, Nature, red blood cells, ribavirin
Feb
18
2010
Group of hunters from the Ju/’hoansi tribe in the Namibian Bush/ Stephan C. Schuster
Researchers from Penn State University, the University of New South Wales in Australia, and the Baylor College of Medicine have sequenced the genomes of four individuals from different groups of the click-speaking San of southern Africa, as well as of Bishop Desmond [...]
Tags: Africa, Bushmen, Desmond Tutu, diversity, genome sequencing, San
Feb
16
2010
The candles on your birthday cake tell you how many years you’ve lived through, but they might not be a reflection of your biological age.
Little bits of DNA called telomeres protect the ends of chromosomes. Over time, through repeated rounds of cell division, telomeres get shorter and shorter. Thus, telomere length is a marker of [...]
Tags: aging, Nature Genetics, telomere
Feb
10
2010
Artist’s impression of Inuk based on genetic analysis
Nuka Godfredsen/Nature
Tufts of hair rescued from the permafrost in Greenland and then tucked away in a basement in Denmark for more than 20 years have given scientists their first glimpse into the genetics of an ancient human.
Eske Willerslev and Morten Rasmussen of the Centre for GeoGenetics at the [...]
Tags: Ancient DNA, Greenland, Inuk, Nature, Saqqaq
Feb
09
2010
Faces of America is a four-part series in which Harvard scholar Henry Louis Gates, Jr. uses genealogy and genetics to explore the family histories of 12 renowned Americans in an effort to understand what made the United States the place it is today.
The list of participants includes:
Elizabeth Alexander, professor and poet
Mario Batali, chef
Stephen Colbert, comedian
Louise [...]
Tags: Dr. Mehmet Oz, Elizabeth Alexander, Eva Longoria, Faces of America, Henry Louis Gates Jr., Her Majesty Queen Noor, Kristi Yamaguchi, Louise Erdrich, Malcolm Gladwell, Mario Batali, Meryl Streep, Mike Nichols, PBS, Stephen Colbert, Yo-Yo Ma
Feb
08
2010
There’s no doubt that blood saves lives. According to the Red Cross, in the United States alone about five million people need a total of 14 million pints of blood each year. That’s 38,000 pints every day.
But transfusions are not without their dangers. Among them is transfusion-related acute lung injury (TRALI), a rare but potentially [...]
Tags: blood, blood donation, lung, Nature Medicine, Red Cross, TRALI
Feb
04
2010
Warfarin (Coumadin®) is a blood thinner given to people at high risk for the formation of blood clots due to conditions such as deep vein thrombosis, heart valve disease or replacement, and irregular heart beat. The drug is also given to prevent recurrence of pulmonary embolism, heart attack and stroke.
If too little warfarin is prescribed, [...]
Tags: CDER, CMS, Coumadin, FDA, warfarin